The patient was not receiving any immunoglobulin infusions, dextran or contrast media, which may explain the elevated protein level. Clinical and laboratory review revealed that the patient had a mild acidosis, but there was no other clinical suspicion of a decline in renal function. The only elevated analytes were glucose level (57.3 mmol/L reference interval, 3.0–7.8 mmol/L), likely due to the dextrose infusion, serum creatinine level (179 μmol/L RI, 64–108 μmol/L) and total protein (83 g/L RI, 60–80 g/L), for which there was no obvious explanation. The pathology results suggested a dilution effect typical of an intravenous contaminated sample with low analyte concentrations. At the time of blood sample collection, the patient was being administered 5% dextrose and a bolus dose of piperacillin/tazobactam intravenously. Antibiotics (Basel) 2020 9: 131Ī 79-year old man was treated for an obstructed left kidney and an infection associated with Klebsiella oxytoca. Therapeutic drug monitoring of meropenem and piperacillin in critical illness-experience and recommendations from one year in routine clinical practice. Interference of IgM-lambda paraprotein with biuret-type assay for total serum protein quantification. Tichy M, Friedecky B, Budina M, et al.Interference of dextran in biuret-type assays of serum proteins. Delanghe JR, Hamers N, Taes YE, Libeer JC.Chemistry information sheet: total protein. Biochemical evaluation of kidney disease. Specificity characteristics of 7 commercial creatinine measurement procedures by enzymatic and Jaffe method principles.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |